Assuntos
Adolescente , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Feminino , Humanos , Derrame Pleural Maligno/diagnóstico , Derrame Pleural Maligno/tratamento farmacológico , Derrame Pleural Maligno/etiologia , Prognóstico , Radiografia Torácica , Rabdomiossarcoma/complicações , Rabdomiossarcoma/tratamento farmacológico , Tomografia Computadorizada por Raios XRESUMO
The effects of estrogen (OVX-EB) and progesterone (OVX-P) administration to ovariectomized (OVX) rats on food and fluid intakes were studied in fifty five animals grouped into three series. Animals in each series were given a choice of two fluids viz. tap water and either 5% glucose (5 G/W) or 12% glucose (12 G/W) or 1.5% Sodium chloride (S/W) by two bottle preference. Both hormones had a differential effect on the ingestion of the two concentrations of glucose while progesterone markedly increased the intake of Sodium Chloride. Could the putative role of the ovarian hormones be hedonic for glucose and homeostatic for salt?
Assuntos
Animais , Peso Corporal/efeitos dos fármacos , Ingestão de Líquidos/efeitos dos fármacos , Ingestão de Alimentos/efeitos dos fármacos , Ingestão de Energia/efeitos dos fármacos , Estrogênios/farmacologia , Feminino , Preferências Alimentares/fisiologia , Glucose/administração & dosagem , Ovariectomia , Ovário/fisiologia , Progesterona/farmacologia , Ratos , Ratos Wistar , Cloreto de Sódio/administração & dosagem , Paladar/fisiologiaRESUMO
The probable roles of Acetylcholine (Ach) and Dopamine (DA) in the modulation of instinctual behaviors of feeding and hoarding (HS), as also the body weight and vaginal cyclicity (EI), were studied by instillation of Atropine (Ach antagonist), Haloperidol (DA antagonist) and Apomorphine (DA agonist) in the dorsal hippocampus of nonpregnant female rats. It was observed that the HS was significantly decreased with both Atropine and haloperidol and increased with Apomorphine, although the food intake was decreased with the three chemicals. It appears that action of both Ach and DA on the dorsal hippocampus has a positive influence on hoarding behavior.
Assuntos
Acetilcolina/fisiologia , Animais , Apomorfina/farmacologia , Atropina/farmacologia , Comportamento Animal/efeitos dos fármacos , Peso Corporal/efeitos dos fármacos , Dopamina/fisiologia , Ingestão de Alimentos/efeitos dos fármacos , Estro/efeitos dos fármacos , Feminino , Haloperidol/farmacologia , Hipocampo/efeitos dos fármacos , RatosRESUMO
Instinctual behaviors of feeding (food intake) and hoarding (HS) so also the body weight and estrus cycles (EI) were studied before and after discrete bilateral electrolytic lesions of dorsal hippocampus in female rats. Following the lesions, there was significant increase in food intake, body weight, hoarding score and disruption of 4-5 days estrus cycles with EI of more than one, as compared to the control (prelesioned) period and the sham operated rats. Lesions of ventral hippocampus in the earlier study (Indian J exp Biol, 26 (1988) 53) had shown a significant decrease in hoarding thus suggesting a differential role of the hippocampus probably mediated through the amygdala and/or hypothalamus both of which either alone or together exert a more direct and pivotal control in the feeding and hoarding behaviour.
Assuntos
Animais , Comportamento Animal , Peso Corporal , Estro , Comportamento Alimentar , Feminino , Hipocampo/fisiologia , RatosAssuntos
Animais , Comportamento Animal , Feminino , Hipocampo/fisiologia , Ratos , Substância Negra/fisiologiaRESUMO
The drive for hoarding food pellets was studied in adult female rats kept on restricted food schedule, by using varying current strength applied through the metal grid. It was observed that the rats maintained higher hoarding score at proestrus and lowest at diestrus at all strengths of currents used in the experiment indicating stronger drive at proestrus.
Assuntos
Animais , Estro , Comportamento Alimentar/fisiologia , Feminino , Privação de Alimentos/fisiologia , Motivação/fisiologia , RatosRESUMO
The adult female rats hoard large quantities of food during proestrus and continue hoarding if ovariectomised at proestrus (Group I). The hoarding score is lowest in diestrus and continue to remain low if ovariectomised during this phase (Group II). The scores in Group I and Group II are reversed in intracerebral administration of Progesterone and Estradiol Benzoate respectively into preoptic areas. The significance of the response is discussed on the basis of built-in feedback mechanism for hoarding cyclicity.
Assuntos
Animais , Castração , Estradiol/farmacologia , Estro , Retroalimentação , Comportamento Alimentar/fisiologia , Feminino , Hormônios Esteroides Gonadais/fisiologia , Injeções Intraventriculares , Ovário/fisiologia , Gravidez , Progesterona/farmacologia , RatosRESUMO
Hoarding pattern studied in 28 adult female albino rats indicated cyclic changes in hoarding corresponding to alterations in estrus cycle. It was observed that the hoarding score was maximum at proestrus and the least at diestrus. Animals ovariectomised at proestrus maintained higher hoarding score and those ovariectomised at diestrus stablised on lower hoarding score. Progesterone administration reduced the score in high-score group and Oestrogen administration improved the score in low score group. Alterations in ovarian hormone levels were thus observed to influence hoarding pattern in rats.
Assuntos
Animais , Castração , Estro , Comportamento Alimentar/efeitos dos fármacos , Feminino , Hormônios Esteroides Gonadais/fisiologia , Gravidez , Progesterona/farmacologia , RatosRESUMO
The present study revealed that the rats kept on two hour meal schedule hoarded large quantity of food as compared to their hoarding score when kept on food ad lib. Body weights were maintained even though the food intake was slightly reduced. Hunger seems to a stronger drive for hoarding.